Treatment of painful limbs/moving extremities with botulinum toxin type A injections.

doses of opioids. Treatment is often unsatisfactory with few reports of success with sympathetic block, lumbar epidural blocks or epidural spinal cord stimulation [7–9] . We describe herein 2 patients with PLMT in whom analgesic multipharmacy failed to relieve their severe lower limb pain. On the other hand treatment with Botulinum toxin type A (Botox , Allergan, Inc.) resulted in both pain relief and improvement of involuntary movements.